Our expert says:
If th3y make you tired, take them in the morning. Antidepressants vary, but most last in the body around 24 hours or more, otherwise you couldn't take them once a day. If once a day dosage is OK and recommended, then a night-time dose is fine then the highest blood levels and drowsiness will arise at a time when this is helpful
Also, most sidepeffects are worst in the 1st week- 10 days, and then reduce
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