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Question
Posted by: Liza M | 2011/10/27

build up to Roaccutane or just go for it

HI Pharmy

Do isotretinoin patients who are going on high dosages (1.5mg -2mg/kg) normally start with lower dosages to introduce the body to the drug or is it typically the high dosage from the word go? Would there be any benefit to starting lower and steadily increasing until the 2mg/kg is reached - or would it likely make no difference?

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Our expert says:
Expert ImagePharmacist

Hi Liza

Generally the side effects are easier to cope with if one starts with a reasonably small dose, perhaps 0.5mg/kg/day. The dose can be gradually increased over the next few weeks depending on tolerance and its effect on the skin condition. Sometimes it needs to be reduced or even temporarily stopped - Your dermatologist will advise you.

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Our users say:
Posted by: pharmacist | 2011/10/31

Hi Liza

Generally the side effects are easier to cope with if one starts with a reasonably small dose, perhaps 0.5mg/kg/day. The dose can be gradually increased over the next few weeks depending on tolerance and its effect on the skin condition. Sometimes it needs to be reduced or even temporarily stopped - Your dermatologist will advise you.

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