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Question
Posted by: charlotta | 2010/08/25

Bloedtoets

Is die bloedtoets: cytochrome P450 (Cyp450) genotyping test vir depressie in s.a. beskikbaar en is dit effektief?
Dankie

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Our expert says:
Expert ImageCyberShrink

Absolutely not at all. There is NO useful test for depression, and anyone who sells you that idea is acting fraudulently. A wide range of drugs, including some antidepressants, can be affected by Cytochrome p450 in their metabolism, and this may be relevant in planning treatment - but nobody with any repute or authority suggests measuring this in a blood test as a test for Depression ( for which purpose it would be useless ).
It can account for some problems in drug interactions, toxocity problems, or reduced effectiveness of some drugs in some situations. There are some 6 different versions of the enzyme. It may help to explain why some of us respond differently to paticular drugs, and why we differ in the unwanted effects we experience.
But there is NO chemical test for the presence of Depression - a good diagnosis ca only be made after a properly trained clinician interviews and assess the individual in person

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Our users say:
Posted by: cybershrink | 2010/08/25

Absolutely not at all. There is NO useful test for depression, and anyone who sells you that idea is acting fraudulently. A wide range of drugs, including some antidepressants, can be affected by Cytochrome p450 in their metabolism, and this may be relevant in planning treatment - but nobody with any repute or authority suggests measuring this in a blood test as a test for Depression ( for which purpose it would be useless ).
It can account for some problems in drug interactions, toxocity problems, or reduced effectiveness of some drugs in some situations. There are some 6 different versions of the enzyme. It may help to explain why some of us respond differently to paticular drugs, and why we differ in the unwanted effects we experience.
But there is NO chemical test for the presence of Depression - a good diagnosis ca only be made after a properly trained clinician interviews and assess the individual in person

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