Our expert says:
Möbius' syndrome (congenital facial paralysis) and limb defects have occurred in the infants of women who have taken misoprostol during the first trimester in an unsuccessful attempt to induce abortion.The absolute risk of this syndrome is probably low among all women exposed to misoprostol in the first trimester. In a recent study of 4673 malformed infants and 4980 control infants, the Latin American Collaborative Study of Congenital Malformations noted an increased frequency of transverse limb defects, ring-shaped constrictions of the extremities, arthrogryposis, hydrocephalus, holoprosencephaly, and exstrophy of the bladder, but not Möbius' syndrome, in infants exposed to misoprostol in utero.
Most of these abnormalities should show up on a scan at 20 weeks. It is important that you tell your doctor so that you can be referred for a detailed scan.
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